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An NIH-Funded Rare Diseases Clinical Research Network Consortium

Latest News

Establishing the First-Ever Spastic Paraplegia Research Consortium

The Spastic Paraplegia Centers of Excellence Research Network is building the foundation for transformative progress in hereditary spastic paraplegia.

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SP-CERN patients, families, and investigators gathering together.

Rare Research Report: July 2026

July 29, 2026

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Mapping the Natural History of Patients with Hereditary Spastic Paraplegia Type 4

June 15, 2026

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Genotype-Structure-Phenotype Correlations Define Divergent Natural Histories in SPG4

Rare Research Report: May 2026

May 14, 2026

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Rare Research Report: April 2026

April 27, 2026

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Rare Research Report: March 2026

March 23, 2026

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The Spastic Paraplegia Centers of Excellence Research Network (SP-CERN) is part of the Rare Diseases Clinical Research Network (RDCRN), which is funded by the National Institutes of Health (NIH) and led by the National Center for Advancing Translational Sciences (NCATS) through its Division of Rare Diseases Research Innovation (DRDRI). SP-CERN is funded under grant number U54NS148312 as a collaboration between NCATS, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Human Genome Research Institute (NHGRI), and the National Institute of Neurological Disorders and Stroke (NINDS). This website is hosted by the network’s Data Management and Coordinating Center at Cincinnati Children’s Hospital Medical Center, which is funded by NCATS and the National Institute of Neurological Disorders and Stroke (NINDS) under grant number TR002818. The content of this website is solely the responsibility of the SP-CERN administrative coordinating center at Boston Children's Hospital and does not necessarily represent the official views of the NIH.

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